What it's used for
Allopurinol is used to manage signs and symptoms of primary or secondary gout. It is also prescribed for patients receiving cancer therapy who have elevated uric acid levels, and for adults with recurrent calcium oxalate stones.
Source: U.S. FDA-approved prescribing information (openFDA).
Typical dosing
For patients with normal kidney function, the initial oral dosage is 100 mg daily.
Dosing shown here is the general FDA-labeled range. Your prescribing clinician determines the exact dose, form, and schedule for you — this is not a substitute for medical advice.
Common side effects
Known adverse reactions include skin rashes, hypersensitivity reactions, kidney toxicity, liver toxicity, and decreased bone marrow function.
Covered strengths on the Tab $0 list
Covered at $0 with an active Tab membership when filled at a participating pharmacy nationwide or through mail order. A licensed clinician must prescribe the medication.
Related medications
Other everything else medications covered at $0 with an active Tab membership.
Allopurinol cost without insurance
Cash prices for Allopurinol without insurance vary widely by pharmacy, strength and quantity — the same prescription can cost very different amounts at two pharmacies in the same town. That is the problem a membership solves.
Allopurinol is on Tab's covered $0 generic list. With an active Tab membership, every covered strength is $0 — not a percentage off, not a coupon that changes month to month — at participating pharmacies nationwide or through mail order. You do not need insurance, and Tab works whether or not you have a health plan.
Tab is a membership, not insurance. Covered medications require a prescription from a licensed clinician.
Allopurinol dosage and administration
Gout : Prior to initiating treatment assess serum uric acid level, complete blood count, chemistry panel, liver and kidney function tests. Prophylactic treatment for gout flares is recommended. ( 2.1 , 2.2 ) Patients with normal kidney function: Initial dosage is 100 mg orally daily. Increase by 100 mg weekly increments until serum uric acid of 6 mg/dl or less is reached (maximum 800 mg daily). ( 2.3 ) Patients with impaired kidney function: The initial dosage is 50 mg orally daily. Follow recommendations for titration in patients with renal impairment until target serum uric acid level is reached. ( 2.6 ) See complete information in the Full Prescribing Information (FPI). Hyperuricemia Associated with Cancer Therapy : The recommended dosage is: Adults: 300 mg to 800 mg orally daily.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Your prescribing clinician decides the exact dose, form and schedule for you — this is not medical advice.
Allopurinol side effects
The following clinically significant adverse reactions are described elsewhere in the labeling: Skin Rash and Hypersensitivity [see Warnings and Precautions ( 5.1 )] Nephrotoxicity [see Warnings and Precautions ( 5.3 )] Hepatoxicity [see Warnings and Precautions ( 5.4 )] Myelosuppression [see Warnings and Precautions ( 5.5 )] Potential Effect on Driving and Use of Machinery [see Warnings and Precautions ( 5.6 )] The following adverse reactions associated with the use of allopurinol tablets were identified in literature, unpublished clinical trials or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. This is not a complete list. Report side effects to your clinician, and seek care for anything severe or unexpected.
Allopurinol drug interactions
The following drugs may increase the risk of serious skin reactions: bendamustine, thiazide diuretics, ampicillin and amoxicillin. ( 7.1 ) Capecitabine: Avoid concomitant use. ( 7.2 ) Mercaptopurine or Azathioprine: Reduce mercaptopurine or azathioprine dose as recommended in the respective prescribing information. ( 7.2 ) Pegloticase: Discontinue and refrain from initiating treatment with allopurinol tablets. ( 7.2 ) See FPI for complete list of significant drug interactions. ( 7.2 ) 7.1 Drugs Known to Affect the Occurrence of Skin Rash and Hypersensitivity Concomitant use of the following drugs may increase the risk of skin rash, which may be severe: bendamustine, thiazide diuretics, ampicillin and amoxicillin.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Tell your clinician and pharmacist about every medication, supplement and over-the-counter product you take.
Who should not take allopurinol
Allopurinol tablets are contraindicated in patients with a history of hypersensitivity reaction to allopurinol or to any of the ingredients of allopurinol tablets. Known hypersensitivity to allopurinol or to any of the ingredients of allopurinol tablets.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Whether this medication is appropriate for you is a clinical decision made by your prescribing clinician.
Common questions
Is allopurinol covered at $0 with Tab?
Yes. Allopurinol is on Tab's covered $0 generic list — every covered strength is $0 with an active membership, at participating pharmacies nationwide or by mail order.
Do I need insurance to get allopurinol through Tab?
No. Tab is a membership, not insurance. Covered medications are $0 with an active membership whether or not you have a health plan.
How do I get an allopurinol prescription with Tab?
Book a video visit with a licensed Tab clinician (unlimited visits are included with membership). If it's clinically appropriate, they send the prescription to your chosen participating pharmacy or by mail order.
How much does allopurinol cost without insurance?
Without insurance, retail cash prices for allopurinol vary by pharmacy, strength and quantity. Allopurinol is on Tab's covered $0 generic list, so every covered strength is $0 with an active Tab membership at participating pharmacies nationwide or by mail order.
What is the cheapest way to get allopurinol?
For medications on Tab's covered list, a Tab membership is the cheapest route: covered strengths of allopurinol are $0 with an active membership, and unlimited video visits with a licensed clinician are included, so the visit that produces the prescription is covered too.
What is the usual dose of allopurinol?
Gout : Prior to initiating treatment assess serum uric acid level, complete blood count, chemistry panel, liver and kidney function tests. Prophylactic treatment for gout flares is recommended. ( 2.1 , 2.2 ) Patients with normal kidney function: Initial dosage is 100 mg orally daily. Increase by 100 mg weekly increments until serum uric acid of 6 mg/dl or less is reached (maximum 800 mg daily). (FDA-approved label, retrieved 2026-09-15. Your clinician sets your dose.)
What are the side effects of allopurinol?
The following clinically significant adverse reactions are described elsewhere in the labeling: Skin Rash and Hypersensitivity [see Warnings and Precautions ( 5.1 )] Nephrotoxicity [see Warnings and Precautions ( 5.3 )] Hepatoxicity [see Warnings and Precautions ( 5.4 )] Myelosuppression [see Warnings and Precautions ( 5.5 )] Potential Effect on Driving and Use of Machinery [see Warnings and Precautions ( 5.6 )] The following adverse reactions associated with the use of allopurinol tablets were identified in literature, unpublished clinical trials or postmarketing reports. (FDA-approved label, retrieved 2026-09-15.)
What interacts with allopurinol?
The following drugs may increase the risk of serious skin reactions: bendamustine, thiazide diuretics, ampicillin and amoxicillin. ( 7.1 ) Capecitabine: Avoid concomitant use. ( 7.2 ) Mercaptopurine or Azathioprine: Reduce mercaptopurine or azathioprine dose as recommended in the respective prescribing information. ( 7.2 ) Pegloticase: Discontinue and refrain from initiating treatment with allopurinol tablets. (FDA-approved label, retrieved 2026-09-15. Tell your clinician about every medication and supplement you take.)
Allopurinol is $0 on the covered list
Members pay $0 for covered generics at participating pharmacies nationwide or by mail order — plus unlimited virtual primary care, urgent care and dermatology visits. No insurance needed.
Solo $49/mo · Family $119/mo for up to 4 people · Family+ $149/mo for up to 8
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