What it's used for
Digoxin is a cardiac glycoside used to treat mild to moderate heart failure in adults, increase heart contraction strength in pediatric heart failure patients, and control resting heart rate in adults with chronic atrial fibrillation.
Source: U.S. FDA-approved prescribing information (openFDA).
Typical dosing
The dose is determined based on patient-specific factors including age, lean body weight, and renal function.
Dosing shown here is the general FDA-labeled range. Your prescribing clinician determines the exact dose, form, and schedule for you — this is not a substitute for medical advice.
Common side effects
Adverse reactions occur in 5% to 20% of patients, with about half involving cardiac toxicity, one-fourth involving digestive issues, and one-fourth involving nervous system or other toxicities.
Covered strengths on the Tab $0 list
Covered at $0 with an active Tab membership when filled at a participating pharmacy nationwide or through mail order. A licensed clinician must prescribe the medication.
Related medications
Other heart, blood pressure & cholesterol medications covered at $0 with an active Tab membership.
Digoxin cost without insurance
Cash prices for Digoxin without insurance vary widely by pharmacy, strength and quantity — the same prescription can cost very different amounts at two pharmacies in the same town. That is the problem a membership solves.
Digoxin is on Tab's covered $0 generic list. With an active Tab membership, every covered strength is $0 — not a percentage off, not a coupon that changes month to month — at participating pharmacies nationwide or through mail order. You do not need insurance, and Tab works whether or not you have a health plan.
Tab is a membership, not insurance. Covered medications require a prescription from a licensed clinician.
Digoxin dosage and administration
2 DOSAGE & ADMINISTRATION Digoxin dose is based on patient-specific factors (age, lean body weight, renal function, etc.). See full prescribing information. Monitor for toxicity and therapeutic effect. 2.1 Important Dosing and Administration Information In selecting a digoxin dosing regimen, it is important to consider factors that affect digoxin blood levels (e.g., body weight, age, renal function, concomitant drugs) since toxic levels of digoxin are only slightly higher than therapeutic levels. Dosing can be either initiated with a loading dose followed by maintenance dosing if rapid titration is desired or initiated with maintenance dosing without a loading dose. Consider interruption or reduction in digoxin dose prior to electrical cardioversion [see Warnings and Precautions (5.4) ] .
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Your prescribing clinician decides the exact dose, form and schedule for you — this is not medical advice.
Digoxin side effects
The following adverse reactions are included in more detail in the Warnings and Precautions section of the label: Cardiac arrhythmias [see Warnings and Precautions (5.1 , 5.2 )] Digoxin Toxicity [see Warnings and Precautions (5.3) ] The overall incidence of adverse reactions with digoxin has been reported as 5-20%, with 15-20% of adverse events considered serious. Cardiac toxicity accounts for about one-half, gastrointestinal disturbances for about one-fourth, and CNS and other toxicity for about one-fourth of these adverse events. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Oliva Therapeutics at 1-877-200-6088 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. This is not a complete list. Report side effects to your clinician, and seek care for anything severe or unexpected.
Digoxin drug interactions
Digoxin has a narrow therapeutic index, increased monitoring of serum digoxin concentrations and for potential signs and symptoms of clinical toxicity is necessary when initiating, adjusting, or discontinuing drugs that may interact with digoxin. Prescribers should consult the prescribing information of any drug which is co-prescribed with digoxin for potential drug interaction information. PGP Inducers/Inhibitors: Drugs that induce or inhibit PGP have the potential to alter digoxin pharmacokinetics. ( 7.1 ) The potential for drug-drug interactions must be considered prior to and during drug therapy. See full prescribing information. ( 7.2 , 7.3 , 12.3 ) 7.1 P-Glycoprotein (PGP) Inducers/Inhibitors Digoxin is a substrate of P-glycoprotein, at the level of intestinal absorption, renal tubular section and biliary–intestinal secretion.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Tell your clinician and pharmacist about every medication, supplement and over-the-counter product you take.
Who should not take digoxin
Digoxin is contraindicated in patients with: Ventricular fibrillation [see Warnings and Precautions (5.1)] Known hypersensitivity to digoxin (reactions seen include unexplained rash, swelling of the mouth, lips or throat or a difficulty in breathing). A hypersensitivity reaction to other digitalis preparations usually constitutes a contraindication to digoxin. Ventricular fibrillation. ( 4 ) Known hypersensitivity to digoxin or other forms of digitalis. ( 4 )
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Whether this medication is appropriate for you is a clinical decision made by your prescribing clinician.
Common questions
Is digoxin covered at $0 with Tab?
Yes. Digoxin is on Tab's covered $0 generic list — every covered strength is $0 with an active membership, at participating pharmacies nationwide or by mail order.
Do I need insurance to get digoxin through Tab?
No. Tab is a membership, not insurance. Covered medications are $0 with an active membership whether or not you have a health plan.
How do I get a digoxin prescription with Tab?
Book a video visit with a licensed Tab clinician (unlimited visits are included with membership). If it's clinically appropriate, they send the prescription to your chosen participating pharmacy or by mail order.
How much does digoxin cost without insurance?
Without insurance, retail cash prices for digoxin vary by pharmacy, strength and quantity. Digoxin is on Tab's covered $0 generic list, so every covered strength is $0 with an active Tab membership at participating pharmacies nationwide or by mail order.
What is the cheapest way to get digoxin?
For medications on Tab's covered list, a Tab membership is the cheapest route: covered strengths of digoxin are $0 with an active membership, and unlimited video visits with a licensed clinician are included, so the visit that produces the prescription is covered too.
What is the usual dose of digoxin?
2 DOSAGE & ADMINISTRATION Digoxin dose is based on patient-specific factors (age, lean body weight, renal function, etc.). See full prescribing information. Monitor for toxicity and therapeutic effect. (FDA-approved label, retrieved 2026-09-15. Your clinician sets your dose.)
What are the side effects of digoxin?
The following adverse reactions are included in more detail in the Warnings and Precautions section of the label: Cardiac arrhythmias [see Warnings and Precautions (5.1 , 5.2 )] Digoxin Toxicity [see Warnings and Precautions (5.3) ] The overall incidence of adverse reactions with digoxin has been reported as 5-20%, with 15-20% of adverse events considered serious. (FDA-approved label, retrieved 2026-09-15.)
What interacts with digoxin?
Digoxin has a narrow therapeutic index, increased monitoring of serum digoxin concentrations and for potential signs and symptoms of clinical toxicity is necessary when initiating, adjusting, or discontinuing drugs that may interact with digoxin. Prescribers should consult the prescribing information of any drug which is co-prescribed with digoxin for potential drug interaction information. (FDA-approved label, retrieved 2026-09-15. Tell your clinician about every medication and supplement you take.)
Digoxin is $0 on the covered list
Members pay $0 for covered generics at participating pharmacies nationwide or by mail order — plus unlimited virtual primary care, urgent care and dermatology visits. No insurance needed.
Solo $49/mo · Family $119/mo for up to 4 people · Family+ $149/mo for up to 8
Start your membership → Compare plansTab is a membership and prescription-discount program, not insurance. A licensed clinician must prescribe any medication. Cancel anytime — no renewal.