What it's used for
This medication is used as replacement or supplemental therapy for hypothyroidism from various causes.
Source: U.S. FDA-approved prescribing information (openFDA).
Typical dosing
Dosing must be individualized based on patient response and laboratory test results.
Dosing shown here is the general FDA-labeled range. Your prescribing clinician determines the exact dose, form, and schedule for you — this is not a substitute for medical advice.
Boxed warning / key safety info
Thyroid hormones are ineffective for weight loss in patients with normal thyroid function and should not be used for obesity.
Common side effects
Side effects are rare and typically only occur if the medication is taken in excessive amounts leading to hyperthyroidism.
Covered strengths on the Tab $0 list
Covered at $0 with an active Tab membership when filled at a participating pharmacy nationwide or through mail order. A licensed clinician must prescribe the medication.
Related medications
Other everything else medications covered at $0 with an active Tab membership.
Liothyronine cost without insurance
Cash prices for Liothyronine without insurance vary widely by pharmacy, strength and quantity — the same prescription can cost very different amounts at two pharmacies in the same town. That is the problem a membership solves.
Liothyronine is on Tab's covered $0 generic list. With an active Tab membership, every covered strength is $0 — not a percentage off, not a coupon that changes month to month — at participating pharmacies nationwide or through mail order. You do not need insurance, and Tab works whether or not you have a health plan.
Tab is a membership, not insurance. Covered medications require a prescription from a licensed clinician.
Liothyronine dosage and administration
Administer liothyronine sodium tablets orally once daily and individual dosage according to patient response and laboratory findings ( 2.1 ) See full prescribing information for recommended dosage for hypothyroidism ( 2.2 ) TSH suppression in well-differentiated thyroid cancer ( 2.3 ) and for thyroid suppression test ( 2.4 ) When switching a patient to liothyronine sodium tablets, discontinue levothyroxine therapy and initiate liothyronine sodium tablets at a low dosage.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Your prescribing clinician decides the exact dose, form and schedule for you — this is not medical advice.
Liothyronine side effects
Adverse reactions associated with liothyronine sodium tablets therapy are primarily those of hyperthyroidism due to therapeutic overdosage [see Warnings and Precautions (5.4) and Overdosage (10) ] .
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. This is not a complete list. Report side effects to your clinician, and seek care for anything severe or unexpected.
Liothyronine drug interactions
See full prescribing information for drugs that affect thyroid hormone pharmacokinetics and metabolism (e.g., absorption, synthesis, secretion, catabolism, protein binding, and target tissue response) and may alter the therapeutic response to liothyronine sodium tablets ( 7 ) 7.1 Drugs Known to Affect Thyroid Hormone Pharmacokinetics Many drugs can exert effects on thyroid hormone pharmacokinetics (e.g. absorption, synthesis, secretion, catabolism, protein binding, and target tissue response) and may alter the therapeutic response to liothyronine sodium tablets (see Tables 1 – 4). Table 1: Drugs That May Decrease T3 Absorption (Hypothyroidism) Potential impact: Concurrent use may reduce the efficacy of liothyronine sodium tablets by binding and delaying or preventing absorption, potentially resulting in hypothyroidism.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Tell your clinician and pharmacist about every medication, supplement and over-the-counter product you take.
Who should not take liothyronine
Liothyronine sodium tablets are contraindicated in patients with uncorrected adrenal insufficiency [see Warnings and Precautions (5.3) ] . Uncorrected adrenal cortical insufficiency ( 4 )
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Whether this medication is appropriate for you is a clinical decision made by your prescribing clinician.
Common questions
Is liothyronine covered at $0 with Tab?
Yes. Liothyronine is on Tab's covered $0 generic list — every covered strength is $0 with an active membership, at participating pharmacies nationwide or by mail order.
Do I need insurance to get liothyronine through Tab?
No. Tab is a membership, not insurance. Covered medications are $0 with an active membership whether or not you have a health plan.
How do I get a liothyronine prescription with Tab?
Book a video visit with a licensed Tab clinician (unlimited visits are included with membership). If it's clinically appropriate, they send the prescription to your chosen participating pharmacy or by mail order.
How much does liothyronine cost without insurance?
Without insurance, retail cash prices for liothyronine vary by pharmacy, strength and quantity. Liothyronine is on Tab's covered $0 generic list, so every covered strength is $0 with an active Tab membership at participating pharmacies nationwide or by mail order.
What is the cheapest way to get liothyronine?
For medications on Tab's covered list, a Tab membership is the cheapest route: covered strengths of liothyronine are $0 with an active membership, and unlimited video visits with a licensed clinician are included, so the visit that produces the prescription is covered too.
What is the usual dose of liothyronine?
Administer liothyronine sodium tablets orally once daily and individual dosage according to patient response and laboratory findings ( 2.1 ) See full prescribing information for recommended dosage for hypothyroidism ( 2.2 ) TSH suppression in well-differentiated thyroid cancer ( 2.3 ) and for thyroid suppression test ( 2.4 ) When switching a patient to liothyronine sodium tablets, discontinue levothyroxine therapy and initiate liothyronine sodium tablets at a low dosage. (FDA-approved label, retrieved 2026-09-15. Your clinician sets your dose.)
What are the side effects of liothyronine?
Adverse reactions associated with liothyronine sodium tablets therapy are primarily those of hyperthyroidism due to therapeutic overdosage [see Warnings and Precautions (5.4) and Overdosage (10) ] . (FDA-approved label, retrieved 2026-09-15.)
What interacts with liothyronine?
See full prescribing information for drugs that affect thyroid hormone pharmacokinetics and metabolism (e.g., absorption, synthesis, secretion, catabolism, protein binding, and target tissue response) and may alter the therapeutic response to liothyronine sodium tablets ( 7 ) 7.1 Drugs Known to Affect Thyroid Hormone Pharmacokinetics Many drugs can exert effects on thyroid hormone pharmacokinetics (e.g. (FDA-approved label, retrieved 2026-09-15. Tell your clinician about every medication and supplement you take.)
Liothyronine is $0 on the covered list
Members pay $0 for covered generics at participating pharmacies nationwide or by mail order — plus unlimited virtual primary care, urgent care and dermatology visits. No insurance needed.
Solo $49/mo · Family $119/mo for up to 4 people · Family+ $149/mo for up to 8
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