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Tretinoin

Tretinoin is a covered generic medication on Tab's $0 list. Here's what it's used for, typical dosing, and side effects, sourced from FDA-approved drug labeling.

$0 with active Tab membership Topical Retinoid [EPC]

What it's used for

See full FDA prescribing information for indications.

Source: U.S. FDA-approved prescribing information (openFDA).

Typical dosing

See full FDA prescribing information for dosing.

Dosing shown here is the general FDA-labeled range. Your prescribing clinician determines the exact dose, form, and schedule for you — this is not a substitute for medical advice.

Common side effects

See full FDA prescribing information for the complete adverse reaction profile.

Covered strengths on the Tab $0 list

Tretinoin 0.025% Gel

Covered at $0 with an active Tab membership when filled at a participating pharmacy nationwide or through mail order. A licensed clinician must prescribe the medication.

Related medications

Other everything else medications covered at $0 with an active Tab membership.

Tretinoin cost without insurance

Cash prices for Tretinoin without insurance vary widely by pharmacy, strength and quantity — the same prescription can cost very different amounts at two pharmacies in the same town. That is the problem a membership solves.

Tretinoin is on Tab's covered $0 generic list. With an active Tab membership, every covered strength is $0 — not a percentage off, not a coupon that changes month to month — at participating pharmacies nationwide or through mail order. You do not need insurance, and Tab works whether or not you have a health plan.

Tab is a membership, not insurance. Covered medications require a prescription from a licensed clinician.

Tretinoin dosage and administration

• The recommended dosage of tretinoin capsules is 22.5 mg/m 2 orally twice daily until complete remission. ( 2.2 ) • Discontinue 30 days after achievement of complete remission or after 90 days of treatment, whichever occurs first. ( 2.2 ) 2.1 Important Safety Information Verify pregnancy status in females of reproductive potential prior to initiating tretinoin capsules. Females of reproductive potential must have a negative pregnancy test before initiating tretinoin capsules [see Use in Specific Populations (8.3)] . 2.2 Recommended Dosage The recommended dosage of tretinoin capsules is 22.5 mg/m 2 orally twice daily until complete remission is documented. Discontinue tretinoin capsules 30 days after achievement of complete remission or after 90 days of treatment, whichever occurs first.

Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Your prescribing clinician decides the exact dose, form and schedule for you — this is not medical advice.

Tretinoin side effects

The following clinically significant adverse reactions are described elsewhere in the labeling: • Differentiation Syndrome [see Warnings and Precautions ( 5.2 )] • Leukocytosis [see Warnings and Precautions ( 5.4 )] • Intracranial hypertension [see Warnings and Precautions (5.5)] • Lipid abnormalities [see Warnings and Precautions ( 5.6 )] • Hepatotoxicity [see Warnings and Precautions ( 5.7 )] • Thromboembolic events [see Warnings and Precautions (5 .8 )] The most common adverse reactions (≥30%) are headache, fever, skin/mucous membrane dryness, bone pain, malaise, shivering, upper respiratory tract disorders, dyspnea, hemorrhage, infections, nausea/vomiting, rash, peripheral edema, leukocytosis, pain, gastrointestinal hemorrhage, chest discomfort, abdominal pain ( 6.1 ).

Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. This is not a complete list. Report side effects to your clinician, and seek care for anything severe or unexpected.

Tretinoin drug interactions

• Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. ( 7.1 ) • Concomitant Use of Products Known to Cause Intracranial Hypertension : Avoid concomitant use with other products that can cause intracranial hypertension. ( 7.2 ) • Vitamin A : Avoid concomitant use with vitamin A. ( 7.3 ) • Anti-fibrinolytic Agents : Avoid concomitant use with anti-fibrinolytic agents. ( 7.4 ) 7.1 Effects of Other Drugs on Tretinoin Capsules Strong or moderate CYP3A Inhibitors Avoid concomitant use of tretinoin capsules with strong CYP3A inhibitors if possible and monitor more frequently if concomitant use is unavoidable. Monitor patients taking moderate CYP3A inhibitors concomitantly with tretinoin capsules more frequently for adverse reactions. Tretinoin is a CYP3A substrate.

Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Tell your clinician and pharmacist about every medication, supplement and over-the-counter product you take.

Who should not take tretinoin

Tretinoin capsules are contraindicated in patients with a known hypersensitivity to tretinoin capsules, any of its components, or other retinoids. Reactions have included rash, pruritus, face edema, and dyspnea [see Adverse Reactions ( 6.1 )]. Hypersensitivity to tretinoin capsules, any of its components, or other retinoids

Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Whether this medication is appropriate for you is a clinical decision made by your prescribing clinician.

Common questions

Is tretinoin covered at $0 with Tab?

Yes. Tretinoin is on Tab's covered $0 generic list — every covered strength is $0 with an active membership, at participating pharmacies nationwide or by mail order.

Do I need insurance to get tretinoin through Tab?

No. Tab is a membership, not insurance. Covered medications are $0 with an active membership whether or not you have a health plan.

How do I get a tretinoin prescription with Tab?

Book a video visit with a licensed Tab clinician (unlimited visits are included with membership). If it's clinically appropriate, they send the prescription to your chosen participating pharmacy or by mail order.

How much does tretinoin cost without insurance?

Without insurance, retail cash prices for tretinoin vary by pharmacy, strength and quantity. Tretinoin is on Tab's covered $0 generic list, so every covered strength is $0 with an active Tab membership at participating pharmacies nationwide or by mail order.

What is the cheapest way to get tretinoin?

For medications on Tab's covered list, a Tab membership is the cheapest route: covered strengths of tretinoin are $0 with an active membership, and unlimited video visits with a licensed clinician are included, so the visit that produces the prescription is covered too.

What is the usual dose of tretinoin?

• The recommended dosage of tretinoin capsules is 22.5 mg/m 2 orally twice daily until complete remission. ( 2.2 ) • Discontinue 30 days after achievement of complete remission or after 90 days of treatment, whichever occurs first. ( 2.2 ) 2.1 Important Safety Information Verify pregnancy status in females of reproductive potential prior to initiating tretinoin capsules. (FDA-approved label, retrieved 2026-09-15. Your clinician sets your dose.)

What are the side effects of tretinoin?

The following clinically significant adverse reactions are described elsewhere in the labeling: • Differentiation Syndrome [see Warnings and Precautions ( 5.2 )] • Leukocytosis [see Warnings and Precautions ( 5.4 )] • Intracranial hypertension [see Warnings and Precautions (5.5)] • Lipid abnormalities [see Warnings and Precautions ( 5.6 )] • Hepatotoxicity [see Warnings and Precautions ( 5.7 )] • Thromboembolic events [see Warnings and Precautions (5 .8 )] The most common adverse reactions (≥30%) are headache, fever, skin/mucous membrane dryness, bone pain, malaise, shivering, upper respiratory tract disorders, dyspnea, hemorrhage, infections, nausea/vomiting, rash, peripheral edema, leukocytosis, pain, gastrointestinal hemorrhage, chest discomfort, abdominal pain ( 6.1 ). (FDA-approved label, retrieved 2026-09-15.)

What interacts with tretinoin?

• Strong CYP3A Inhibitors and Inducers: Avoid coadministration with strong CYP3A inhibitors and inducers. ( 7.1 ) • Concomitant Use of Products Known to Cause Intracranial Hypertension : Avoid concomitant use with other products that can cause intracranial hypertension. ( 7.2 ) • Vitamin A : Avoid concomitant use with vitamin A. ( 7.3 ) • Anti-fibrinolytic Agents : Avoid concomitant use with anti-fibrinolytic agents. (FDA-approved label, retrieved 2026-09-15. Tell your clinician about every medication and supplement you take.)

Tab membership

Tretinoin is $0 on the covered list

Members pay $0 for covered generics at participating pharmacies nationwide or by mail order — plus unlimited virtual primary care, urgent care and dermatology visits. No insurance needed.

Solo $49/mo · Family $119/mo for up to 4 people · Family+ $149/mo for up to 8

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Tab is a membership and prescription-discount program, not insurance. A licensed clinician must prescribe any medication. Cancel anytime — no renewal.

Covered generics at $0. Care included.

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Tab is a membership and prescription-discount program—not insurance, and not a substitute for it. $0 pricing applies to medications on the current covered generic list with active membership, at participating pharmacy locations nationwide or through mail order, and is subject to change. Mail-order home delivery is preferred for recurring prescriptions; activation, availability, and delivery timing apply. This page is for general reference, drawn from FDA-approved drug labeling, and is not medical advice. Only a licensed clinician can determine if a medication is right for you.